Blade has his martial arts skills but less experience in battle overall, and i think Lucian is more ruthless, Blade controls his actions more, he doesn't let his animalistic side lose as much as Lucian does, but i know what you mean. It is a very close fight.
Overall, sure. But like I said, there are diminishing returns in regards to "experience". And Blade has more relevant recent experience. He basically spends all day everyday tracking/fighting vampires, often in hand-to-hand. When he's not doing that, he's training to do it.
Lucian, on the other hand, has spent much of the last hundred years as a leader in a guerrilla battle against vampires, rather than constantly fighting them head-to-head. And besides, if the first Underworld film is any indication werewolves transitioned to firearms as their staple weapon long ago.
And I don't know if letting the animalistic side go is necessarily a good thing in the context of a fight, as it can potentially make you predictable and sloppy. Blade is plenty ruthless -- remember him torturing vamps/familiars for information? Or occasionally leaving civilians to die? Of particular note is his speech to Dr. Jenson in the first film -- "You better learn to pull the trigger!" -- after she stopped him from beating/executing the cop familiar.