The Lobo Brothers are two supervillains from Marvel Comics.
The Lobo Brothers first appeared in Spectacular Spider-Man #143 (October 1988), and were created by Gerry Conway and Sal Buscema.
The characters subsequently appear in The Spectacular Spider-Man #146 (January 1989), Web of Spider-Man #47-48 (February-March 1989), The Spectacular Spider-Man #149-150 (April-May 1989), Web of Spider-Man #51 (June 1989), The Spectacular Spider-Man #151-152 (June-July 1989), Web of Spider-Man #53 (August 1989), The Spectacular Spider-Man #154 (September 1989), and Web of Spider-Man #54-55 (September-October 1989).
Carlos Lobo received an entry in the Official Handbook of the Marvel Universe Update '89 #4.
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Official Site: Marvel Comics
Links: Wikipedia Spider-fan.org Appendex to the Marvel Handbook