Mister Sinister is a fictional character that appears in comic books published by Marvel Comics. The character first appeared in Uncanny X-Men #221 (Sept. 1987) and was created by writer Chris Claremont and artist Marc Silvestri.
Debuting in the Modern Age of comic books, the character has appeared in a number of X-Men titles including spin-off and several limited series. The character has also featured in associated Marvel merchandise including animated television series; toy; trading cards and video game.
Writer Chris Claremont conceived Mister Sinister as a new villain for the X-Men, having felt "tired of just going back to Magneto and the Brotherhood of Evil Mutants and the same old same old" Claremont recalled:
Mister Sinister debuted in the title Uncanny X-Men, briefly mentioned by Sabretooth during the Mutant Massacre crossover as the leader of the Marauders who had sent them to slaughter the Morlock population. In the following issue, the X-Men member Psylocke picks up a shadowy mental image of the Marauders' "Master" from Sabretooth's mind. Mister Sinister finally appeared on-panel in issue #221 (Sept. 1987). The character plays a major role in the Inferno crossover, where it is revealed that Sinister cloned Madelyne Pryor from Jean Grey for the purpose of her to mate with Cyclops and produce a child, their son Nathan;
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