Tribbles are fictional animals in the Star Trek universe who first appeared in the episode titled "The Trouble With Tribbles". They are depicted as small, soft, and gentle, and as producing a soothing purr sound. These traits are said to endear them to most sentient races which encounter them, with the notable exception of Klingon, who consider tribbles to be "mortal enemies" of the Klingon Empire, as stated in the Star Trek Deep Space Nine episode "Trials and Tribble-ations".
While appearing in only four episodes and briefly in three of the Star Trek movies, they are one of the most popular and well-known species featured in the Star Trek universe, fairly well known even to casual followers of the series. In 2006, two tribble props from "Trials and Tribble-ations" were auctioned for US $800 – 1,200.
The expression "multiplying like tribbles" has also become commonplace in the context of science fiction or technology.
A family of proteins which have a variety of roles, including involvement in the control of the cell cycle in the fruit fly, was named after these fictional animals.
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Links: Wikipedia Memory Alpha- Tribbles Star Trek.Com- Tribbles